Filoviruses infect a wide range of cell types with the exception of lymphocytes.The intracellular proteins cathepsin B and L, two-pore channel 1 and 2, and bona fide receptor Niemann–Pick Disease C1 (NPC1) are essential for the endosomal phase of cell entry.However, earlier steps of filoviral infection remain poorly characterized.Numerous pla

Schism is the new normal for the bioeconomy concept.Since its proliferation in governments, the concept has been adapted to fit national or regional exigencies.Earlier this century the knowledge-based bioeconomy (KBBE) in Europe was seen as a technical and knowledge fix in the evolving sustainability landscape.At the OECD, the concept was further h

Numerous advantages have been reported on PAC (poly aluminum chloride) used as a coagulant over other coagulants such as alum and ferric chloride used in conventional water treatment process with medium and high turbidity levels.These include lower amounts of PACL required specially in removing turbidity, larger floc grain formation, reduced floc s

In this article, we will investigate a retarded van der Pol-Duffing oscillator with multiple delays.At first, we will find conditions for which Bogdanov-Takens (B-T) bifurcation occurs around the trivial equilibrium of the proposed system.The center manifold Television theory has been used to extract second order normal form of the B-T bifurcation.

IntroductionObesity is a rapidly growing global health concern with considerable negative impact on life-time Lips expectancy.It has yet not been clarified if and how obesity impacts outcomes of severe bacterial infections.The aim of this study was to determine how body mass index impacts outcome of severe bacterial infections in a well-defined pop